Fluorinated Nanocarbon Film Electrode Capable of Signal Amplification for Lipopolysaccharide Detection. (10th April 2016)

• Record Type: Journal Article
• Authors: Oda, Atsumu; Kato, Dai; Yoshioka, Kyoko; Tanaka, Mutsuo; Kamata, Tomoyuki; Todokoro, Masami; Niwa, Osamu
• Is Part Of: Electrochimica acta. Volume 197(2016)
• Page Start: 152
• Page End: 158
• Publication Date: 2016-04-10
• Subjects: nanocarbon film -- surface fluorination -- signal amplification -- lipopolysaccharide -- electrochemical sensors; Electrochemistry -- Periodicals; Electrochemistry, Industrial -- Periodicals; 541.37
• DOI: 10.1016/j.electacta.2015.12.100
• Languages: English
• ISSNs: 0013-4686

Abstract

Abstract: We describe a current amplification system that employs a fluorinated nanocarbon (F-nanocarbon) film electrode formed by unbalanced magnetron (UBM) sputtering with a short CF4 plasma treatment. The F-nanocarbon film exhibited the typical electrochemical reaction of a ferrocene-based mediator while strongly suppressing the electrochemical oxidation of Fe 2+ ions. This selectivity provided the current amplification of ferrocene mediators with Fe 2+ ions solely by using the F-nanocarbon film electrode without interference from the direct oxidation current of Fe 2+ ions. The current amplification system was used to realize an electrochemical biosensor with superior performance for detecting lipopolysaccharides. A detection limit of 2 ng mL −1 with good reproducibility (RSD of 4.2%) was achieved thanks to the very low noise made by possible by the ultraflat and hydrophobic surface.