Plasma cell-rich acute rejection of renal allograft: an unusual case of acute allograft dysfunction. (September 2017)

• Record Type: Journal Article
• Authors: Lee, Kian-Guan; Thangaraju, Sobhana; Ahmed, Syed Salahuddin; Loh, Hwai Liang; Tng, Alvin Ren Kwang; Kee, Terence Yi Shern
• Is Part Of: Proceedings of Singapore healthcare. Volume 26:Number 3(2017)
• Page Start: 200
• Page End: 202
• Publication Date: 2017-09
• Subjects: Plasma cell rejection -- renal transplantation -- renal allograft dysfunction; Medical care -- Singapore -- Periodicals; Medical care; Singapore; Periodicals; 362.1095957
• DOI: 10.1177/2010105816681314
• Languages: English
• ISSNs: 2010-1058

Abstract

We report a case of renal allograft dysfunction due to plasma cell-rich acute rejection (PCAR), which is an uncommon clinical entity with a wide range of differential diagnoses. Extensive diagnostic workup, treatment approach and outcome are discussed and we provide a brief summary of the current management dilemma. Nevertheless, the diagnosis of PCAR portends a poor prognosis and therefore timely diagnosis and intensification of treatment is crucial to prevent disease progression.