Treatment of Neurogenic Cough with Tramadol: A Pilot Study. (July 2017)

• Record Type: Journal Article
• Authors: Dion, Gregory R.; Teng, Stephanie E.; Achlatis, Efstratios; Fang, Yixin; Amin, Milan R.
• Is Part Of: Otolaryngology--head and neck surgery. Volume 157:Number 1(2017)
• Page Start: 77
• Page End: 79
• Publication Date: 2017-07
• Subjects: neurogenic cough -- cough -- tramadol -- neurogenic cough treatment -- neuropathic cough treatment; Head -- Surgery -- Periodicals; Neck -- Surgery -- Periodicals; Otolaryngology -- Periodicals; 617.51
• DOI: 10.1177/0194599817703949
• Languages: English
• ISSNs: 0194-5998

Abstract

This study employs validated cough assessment tools to prospectively determine the impact of tramadol on cough severity and quality of life in subjects with neurogenic cough. The study was a prospective case series with planned data collection at a tertiary care academic medical center laryngology practice. Sixteen consecutive collected subjects with neurogenic cough prospectively completed pre- and posttreatment validated cough assessment tools, the cough severity index (CSI) and Leicester Cough Questionnaire (LCQ). All subjects in the study reported at least some improvement in their cough symptoms. In a Wilcoxon signed rank test that compared paired results, CSI scores improved from 23 to 14 and LCQ scores improved from 74 to 103 ( P = .003 and P = .005, respectively). This small preliminary assessment suggests that tramadol warrants additional evaluation as a treatment for neurogenic cough.