Multi‐Gram Scale Synthesis of 1, 2, 3‐Triazolium Ionic Liquids and Assay of Their Resistance towards Bases. Issue 35 (23rd August 2018)

• Record Type: Journal Article
• Authors: Raiguel, Stijn; Thomas, Joice; Binnemans, Koen; Dehaen, Wim
• Is Part Of: European journal of organic chemistry. Issue 35(2018)
• Page Start: 4850
• Page End: 4856
• Publication Date: 2018-08-23
• Subjects: Ionic liquids -- Green chemistry -- Grignard reaction -- Triazolium salts; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201800925
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : An easily upscalable synthesis method for 1, 2, 3‐triazolium ionic liquids is presented. Several ionic liquids were synthesized and characterized. The influence of the side chain structure on the base‐stability was investigated. One example, functionalized with linear alkyl side chains, was found to exhibit excellent stability against hot concentrated NaOH solutions and Grignard reagents. Abstract : A new, upscalable method for the synthesis of 1, 2, 3‐triazolium ionic liquids is described for scales up to 40+ grams. The influence of various substituents on the stability of these structures towards bases is investigated. One example was found to exhibit noteworthy stability towards NaOH and Grignard reagents.