Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging. (26th May 2016)

• Record Type: Journal Article
• Authors: Ahlborg, M; Kaethner, C; Knopp, T; Szwargulski, P; Buzug, T M
• Is Part Of: Physics in medicine & biology. Volume 61:Number 12(2016:Jun.)
• Page Start: 4583
• Page End: 4598
• Publication Date: 2016-05-26
• Subjects: MPI -- magnetic particle imaging -- image sequences -- image reconstruction; Biophysics -- Periodicals; Medical physics -- Periodicals; 610.153
• DOI: 10.1088/0031-9155/61/12/4583
• Languages: English
• ISSNs: 0031-9155

Abstract

Abstract: The imaging technology magnetic particle imaging allows the detection of magnetic material, in particular superparamagnetic nanoparticles, by remagnetization of the material via magnetic fields. The application is aimed at medical imaging where the particles are applied as tracer directly into the blood stream. Medical safety considerations such as peripheral nerve stimulation limit the maximal amplitude of the magnetic fields and in turn the field of view size. To handle this constraint the concept of patches was introduced, which allows a shift of a field of view to different positions in order to enlarge the imaging area. If this is done statically an overlap of patches can be used to reduce truncation artifacts occurring at the adjacent edges. In this contribution, a differentiation of two different kinds of patch overlaps, i.e. a trajectory and a system matrix overlap, is made. Further, different concepts to combine the resulting redundant information are investigated with respect to the reduction of truncation artifacts. The methods are analyzed in detail in a simulation study and validated on experimental data.