Measurement of carbon ion microdosimetric distributions with ultrathin 3D silicon diodes. (10th May 2016)

• Record Type: Journal Article
• Authors: Gómez, F; Fleta, C; Esteban, S; Quirion, D; Pellegrini, G; Lozano, M; Prezado, Y; Dos Santos, M; Guardiola, C; Montarou, G; Prieto-Pena, J; Pardo-Montero, Juan
• Is Part Of: Physics in medicine & biology. Volume 61:Number 11(2016:Jun.)
• Page Start: 4036
• Page End: 4047
• Publication Date: 2016-05-10
• Subjects: dosimetry -- hadrontherapy -- microdosimetry -- LET -- silicon detectors; Biophysics -- Periodicals; Medical physics -- Periodicals; 610.153
• DOI: 10.1088/0031-9155/61/11/4036
• Languages: English
• ISSNs: 0031-9155

Abstract

Abstract: The commissioning of an ion beam for hadrontherapy requires the evaluation of the biologically weighted effective dose that results from the microdosimetric properties of the therapy beam. The spectra of the energy imparted at cellular and sub-cellular scales are fundamental to the determination of the biological effect of the beam. These magnitudes are related to the microdosimetric distributions of the ion beam at different points along the beam path. This work is dedicated to the measurement of microdosimetric spectra at several depths in the central axis of a 12 C beam with an energy of 94.98 AMeV using a novel 3D ultrathin silicon diode detector. Data is compared with Monte Carlo calculations providing an excellent agreement (deviations are less than 2% for the most probable lineal energy value) up to the Bragg peak. The results show the feasibility to determine with high precision the lineal energy transfer spectrum of a hadrontherapy beam with these silicon devices.