Spectroscopic characterisation of two polyketide metabolites from Cylindrocarpon sp. from driftwood. Issue 1 (2nd January 2018)

• Record Type: Journal Article
• Authors: Yoshida, Seiya; Suzuki, Takuma; Furuno, Hiroshi; Aboshi, Takako; Murayama, Tetsuya; Koseki, Takuya; Shiono, Yoshihito
• Is Part Of: Natural product research. Volume 32:Issue 1(2018)
• Page Start: 60
• Page End: 64
• Publication Date: 2018-01-02
• Subjects: Cylindrocarpon sp -- polyketides -- driftwood -- antimicrobial activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1332616
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new polyketides, (5 R, 7 R, 9 R )-7, 9-dihydroxy-5-decanolide and (4 E, 6 R, 9 R )- 6, 9-dihydroxydec-4-enoic acid (2 ), were isolated from rice cultures of Cylindrocarpon sp. SY-39 discovered during screening of driftwood at a Shonai coast area in Yamagata, Japan. The structures of1 and2 were determined using a variety of spectroscopic methods. Compound2 exhibited moderate antimicrobial activity against Staphylococcus aureus NBRC 13276 and Aspergillus clavatus F 318a at a concentration of 50 μ g per disk. Abstract :