Relationship Between Iodine Concentration in Maternal Colostrum and Neurobehavioral Development of Infants in Shanghai, China. (August 2016)

• Record Type: Journal Article
• Authors: Wu, Meiqin; Wu, Deqing; Wu, Wei; Li, Hui; Cao, Lulu; Xu, Jian; Yu, Xiaodan; Bian, Xiaoyan; Yan, Chonghuai; Wang, Weiye
• Is Part Of: Journal of child neurology. Volume 31:Number 9(2016:Sep.)
• Page Start: 1108
• Page End: 1113
• Publication Date: 2016-08
• Subjects: infants -- iodine nutrition -- lactating -- neurobehavioral development; Nervous system -- Diseases -- Periodicals; 618.928
• DOI: 10.1177/0883073816639378
• Languages: English
• ISSNs: 0883-0738

Abstract

It is well known that iodine plays an important role in the process of early growth and development of most organs, especially the brain. However, iodine concentration in the colostrum and its association with the neurobehavioral development of infants remains unclear. Colostrums from 150 women were collected, and their iodine concentrations were measured. The median colostrum iodine level was 187.8 μg/L. The Bayley Scales of Infant and Toddler Development–III test was performed when the infants were about 18 months. The mean cognitive, language, and motor composite scores were 105.3 ± 9.8, 105.2 ± 11.1, and 104.6 ± 6.7, respectively. And the mean scores of the 5 subtests were 11.1 ± 2.0, 9.3 ± 2.0, 12.4 ± 2.3, 11.1 ± 1.2, and 10.4 ± 1.2, respectively. No statistically significant difference was observed in the cognition, language, or motor development of infants across different levels of colostrum iodine. After adjusting for a range of confounding factors, colostrum iodine concentration was a predictor of motor development, specifically gross motor development.