Front Cover: Responsive Fluorescence Probe for Selective and Sensitive Detection of Hypochlorous Acid in Live Cells and Animals (Chem. Asian J. 18/2018). Issue 18 (23rd August 2018)

• Record Type: Journal Article
• Authors: Feng, Huan; Meng, Qingtao; Wang, Yue; Duan, Chengchen; Wang, Cuiping; Jia, Hongmin; Zhang, Zhiqiang; Zhang, Run
• Is Part Of: Chemistry, an Asian journal. Volume 13:Issue 18(2018)
• Page Start: 2573
• Page End: 2573
• Publication Date: 2018-08-23
• Subjects: imaging agents -- fluorescent probes -- hypochlorous acid -- in vitro -- in vivo; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201801106
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract : Being hyporesponsive : A new responsive fluorescence probe, PQI, is reported for quantitative fluorescence detection of hypochlorous acid (HOCl) in aqueous solution and live organisms.PQI features a large Stokes shift, high sensitivity and selectivity, and rapid fluorescence response towards HOCl. Quantitative detection of HOCl in single live cells was demonstrated through fluorescence imaging and flow cytometry analysis. In vivo sensing and imaging of HOCl in zebrafish and nude mice were achieved by usingPQI as the fluorescence probe. More information can be found in the Full Paper by Qingtao Meng, Run Zhang et al. onpage 2611 in Issue 18, 2018 (DOI:10.1002/asia.201800957 ).