Fosaprepitant for the Treatment of Refractory Postoperative Nausea and Vomiting. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Tran, Linh H.; Cudny, Magdalena; Ngo, Dat; Patel, Samit; Lam, Manuel Y.
• Is Part Of: Hospital pharmacy. Volume 50:Issue 3(2015)
• Page Start: 221
• Page End: 223
• Publication Date: 2015-03
• Subjects: breakthrough -- Emend -- fosaprepitant -- nausea -- postoperative -- refractory -- vomiting; Hospital pharmacies -- Periodicals; Pharmacy Service, Hospital; Hospital pharmacies; Periodicals; Periodicals; 615.1
• DOI: 10.1310/hpj5003-221
• Languages: English
• ISSNs: 0018-5787

Abstract

Postoperative nausea and vomiting (PONV) is a debilitating condition that occurs in approximately 30% of patients undergoing general anesthesia. Premedication with 5-HT3 receptor antagonists and glucocorticoids is effective in clinical practice; however, 10% to 20% of patients still develop PONV. Currently, little is known about the treatment of refractory PONV. We present a case that illustrates the use of fosaprepitant for the treatment of refractory postoperative nausea and vomiting.