Travel-related health problems in the immunocompromised traveller: An exploratory study. Issue 25 (September 2018)

• Record Type: Journal Article
• Authors: van Aalst, Mariëlle; van Ruissen, Marella C.E.; Verhoeven, Roos; de Bree, Godelieve J.; Goorhuis, Abraham; Grobusch, Martin P.
• Is Part Of: Travel medicine and infectious disease. Issue 25(2018)
• Page Start: 50
• Page End: 57
• Publication Date: 2018-09
• Subjects: Travel -- Immunocompromised traveller -- Immunodeficiency -- Travellers' diarrhoea; Travel -- Health aspects -- Periodicals; Communicable diseases -- Periodicals; Tropical medicine -- Periodicals; 610.5
• DOI: 10.1016/j.tmaid.2018.05.005
• Languages: English
• ISSNs: 1477-8939

Abstract

Abstract: Background: Immunocompromised travellers (ICTs) are at increased risk of travel-related health problems. Therefore, they are advised to attend specialised pre-travel clinics for advice on vaccination, malaria chemoprophylaxis and on-demand antibiotics. However, studies yield conflicting data regarding travel-related health problems encountered by ICTs; questioning the rationale for certain advices, and particularly the advice of on-demand antibiotics. Objective: To evaluate self-reported travel-related health problems, antibiotic use, medical visits and risk behaviours in ICTs and controls. Methods: We conducted a questionnaire-based observational study with pilot character. We recruited participants from a (medical) pre-travel clinic. Telephone interviews were conducted 2–4 weeks post-travelling, applying a structured questionnaire. Results: We included 30 ICTs and 30 controls. More ICTs than controls reported travel-related health problems, antibiotic use and medical visits, although not statistically significant. Travellers' diarrhoea appeared to be more severe in ICTs. Furthermore one ICT was hospitalized post-travel due to pneumonia. Of ICTs, 2/30 (7%) used on demand antibiotics while not indicated (according to the protocol of the Dutch national coordinating centre for travel advice or prescribed by a physician). Reversely, 6/30 (20%) did not use on demand antibiotics while actually indicated according to this protocol. Discussion: Our findings substantiate the recommendation of on demand antibiotics. However, ICTs did often not use on demand antibiotics correctly; they therefore need very careful instructions.