Intestinal methane production is associated with decreased weight loss following bariatric surgery. Issue 6 (November 2016)

• Record Type: Journal Article
• Authors: Mathur, Ruchi; Mundi, Manpreet S.; Chua, Kathleen S.; Lorentz, Paul A.; Barlow, Gillian M.; Lin, Eugenia; Burch, Miguel; Youdim, Adrienne; Pimentel, Mark
• Is Part Of: Obesity research & clinical practice. Volume 10:Issue 6(2016:Nov./Dec.)
• Page Start: 728
• Page End: 733
• Publication Date: 2016-11
• Subjects: Bariatric surgery -- Methane -- Breath test -- Methanogen; Obesity -- Research -- Periodicals; Obesity -- Treatment -- Periodicals; Obesity -- Periodicals; Obésité -- Recherche -- Périodiques; Obésité -- Traitement -- Périodiques; Obesity -- Research; Obesity -- Treatment; Electronic journals; Periodicals; 616.398
• DOI: 10.1016/j.orcp.2016.06.006
• Languages: English
• ISSNs: 1871-403X

Abstract

Summary: To determine whether methane and hydrogen on breath test affects weight loss after bariatric surgery, 156 subjects (pre-surgery BMI ≥33) were recruited ≥4 months after surgery. Pre- and post-surgery weights and BMIs were recorded. Post-surgery methane and hydrogen levels were determined. % total weight loss and % change in BMI were prorated to six months after surgery. M+/H+ subjects ( N = 13) exhibited lower prorated % change in BMI vs. all other subjects ( N = 144) ( p = 0.13), and significantly lower prorated % total weight loss ( p = 0.036). These findings may suggest that subjects with positive breath methane and hydrogen lose less weight following bariatric surgery.