Polybrominated diphenyl ethers in human placenta associated with neonatal physiological development at a typical e-waste recycling area in China. (January 2015)

• Record Type: Journal Article
• Authors: Xu, Long; Huo, Xia; Zhang, Yuling; Li, Weiqiu; Zhang, Jianqing; Xu, Xijin
• Is Part Of: Environmental pollution. Volume 196(2015)
• Page Start: 414
• Page End: 422
• Publication Date: 2015-01
• Subjects: PBDEs -- E-waste -- Human placenta -- PDBE exposure -- Neonatal physiological index; Pollution -- Periodicals; Pollution -- Environmental aspects -- Periodicals; Environmental Pollution -- Periodicals; Pollution -- Périodiques; Pollution -- Aspect de l'environnement -- Périodiques; Pollution -- Effets physiologiques -- Périodiques; Pollution; Pollution -- Environmental aspects; Periodicals; Electronic journals; 363.73
• DOI: 10.1016/j.envpol.2014.11.002
• Languages: English
• ISSNs: 0269-7491

Abstract

Abstract: Our aim of this study was to characterize the exposure pattern of polybrominated diphenyl ethers (PBDEs) in human placenta and assess their potential effects on neonates. Placenta samples were obtained from a typical e-waste area in Guiyu and a reference area in Haojiang, China. The median ∑PBDE concentration was 32.25 ng/g lipid weight (lw) in placenta samples from Guiyu, and 5.13 ng/g lw from Haojiang. BDE-209 predominated in placenta samples, followed by BDE-28, -47, -99 -153, -183. Residence in Guiyu contributed the most to elevated PDBE levels. Neonatal physiological indices, including body-mass index (BMI), Apgar1 score and head circumference, were reduced in Guiyu group. No significant difference was found in neonatal weight between the two groups, but neonatal body length in Guiyu was increased. Our data suggest prenatal exposure to PBDEs is high at the e-waste recycling area, and may lead to adverse physiological development in the fetus. Highlights: PBDEs were determined and found to be high in human placenta from an e-waste area. BDE-209 was predominant, followed by BDE-28, -47, -99, -153 and -183. Elevated PBDEs in placenta of exposed residents were related to residence at e-waste sites. Adverse neonatal physiological development may relate to PBDE concentrations. Neonate development may be affected at e-waste sites. Abstract : In utero exposure to PBDEs is high at the e-waste recycling area, which poses a threat to fetal growth and development, and might affect their health in later life.