Adenocarcinoma at the gastroesophageal junction. (29th September 2014)

• Record Type: Journal Article
• Authors: Al‐Haddad, Sahar; Chang, Andrew C.; De Hertogh, Gert; Grin, Andrea; Langer, Rupert; Sagaert, Xavier; Salemme, Marianna; Streutker, Catherine J.; Soucy, Geneviève; Tripathi, Monika; Upton, Melissa P.; Vieth, Michael; Villanacci, Vincenzo
• Other Names: Giuli Robert guestEditor.; Umar Asad guestEditor.
• Is Part Of: Annals of the New York Academy of Sciences. Volume 1325(2014)
• Page Start: 211
• Page End: 225
• Publication Date: 2014-09-29
• Subjects: Her2 -- gastroesophageal junction -- neoadjuvant -- immunohistochemistry -- pyloric gland adenoma -- intestinal metaplasia -- OESO; Medical sciences -- Periodicals; Medicine -- Periodicals; Science -- Periodicals; 610
• DOI: 10.1111/nyas.12535
• Languages: English
• ISSNs: 0077-8923

Abstract

Abstract : The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the clinical differences between carcinomas arising slightly above, slightly below, and within the gastroesophageal junction (GEJ); information provided by biopsies; information provided by resection specimens following neoadjuvant therapy; histologic differences existing between carcinomas arising slightly above, slightly below, and within the GEJ; differences provided by immunohistochemistry in these tumors; information given by endoscopic mucosal resection specimens; the role of esophageal pyloric gland adenomas as precursors of adenocarcinomas in the region of the cardia; the role of pancreatic metaplasia; Her2 immunoreactivity to make distinctions in the site of origin; and intestinal metaplasia limited to the cardia as a precursor of adenocarcinoma.