Incorporation of no-carrier added 200, 203Pb and 200, 201, 202Tl in calcium alginate and hesperidin incorporated calcium alginate beads. (March 2017)

• Record Type: Journal Article
• Authors: Sarkar, Kangkana; Lahiri, Susanta; Sen, Kamalika
• Is Part Of: Applied radiation and isotopes. Volume 121(2017:Mar.)
• Page Start: 16
• Page End: 21
• Publication Date: 2017-03
• Subjects: Hesperidin -- 200, 203Pb -- 200, 201, 202Tl -- Calcium alginate -- Extraction; Radiology -- Periodicals; Radiation -- Industrial applications -- Periodicals; Nuclear chemistry -- Periodicals; Internet resource; Periodical; 660.298
• DOI: 10.1016/j.apradiso.2016.12.022
• Languages: English
• ISSNs: 0969-8043

Abstract

Abstract: When radioisotopes are injected to human body, instantly free radicals are generated due to the interaction of ionizing radiation with water and fluids present in the body. The vehicle carrying radionuclides into human body should therefore be designed in a way which could also eliminate or reduce such possibilities. For the first time we have used free radical scavenger hesperidin, a polyphenolic compound having a benzo-γ-pyrone with a benzene ring moiety for extraction of no-carrier added (NCA) 200, 203 Pb and 200, 201, 202 Tl. We have modified CA beads by incorporation of a polyphenol (hesperidin) (CA-Hes). This tailor made beads were characterized and tested for their efficacy towards extraction of no-carrier-added lead and thallium radioisotopes from 40 MeV α particle irradiated Hg2 Cl2 target. Highlights: Calcium alginate (CA) beads were modified by incorporation of Hesperidin (CA-Hes) Clinically important Pb/Tl radionuclides were produced via Hg2 Cl2 (α, xpyn) reaction Pb/Tl radionuclides were extracted in CA and free radical scavenger CA-Hes beads CA and CA-Hes beads are efficient in separation Pb and Tl radionuclides from Hg