Acquired Immune Deficiency Syndrome–Associated Kaposi Sarcoma in a Child Presenting as a Solitary Plantar Hyperkeratotic Plaque. Issue 4 (July 2017)

• Record Type: Journal Article
• Authors: Grenier, Pierre-Olivier; Auger, Isabelle
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 21:Issue 4(2017:Jul./Aug.)
• Page Start: 348
• Page End: 350
• Publication Date: 2017-07
• Subjects: Kaposi sarcoma -- human immunodeficiency virus -- human herpesvirus 8 -- acquired immune deficiency syndrome; Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.1177/1203475417698696
• Languages: English
• ISSNs: 1203-4754

Abstract

Background and Objective: Acquired immune deficiency syndrome (AIDS)–associated Kaposi sarcoma (KS) among the pediatric population is a rare entity in North America and Europe, and its cutaneous manifestations are not well defined in the literature. The investigators report the case of a boy with an AIDS-associated KS presenting as an infiltrated hyperkeratotic plaque of the plantar arch. Methods and Results: An 11-year-old African boy with congenital human immunodeficiency virus (HIV) had a skin biopsy of the plantar lesion that was consistent with a KS. The patient also presented intestinal and pulmonary symptoms; combined chemotherapy regimen and highly active antiretroviral therapy were given in the presence of systemic involvement. Conclusion: AIDS-associated KS poses a particular challenge to clinical diagnosis, since it can manifest with a variety of lesions. Dermatologists should have a low threshold for performing a skin biopsy in patients with HIV.