Case Report of Calciphylaxis Secondary to Calcium and Vitamin D3 Supplementation. Issue 2 (March 2017)

• Record Type: Journal Article
• Authors: Storan, Eoin R.; O'Gorman, Susan M.; Murphy, Annette; Laing, Mary
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 21:Issue 2(2017:Mar./Apr.)
• Page Start: 162
• Page End: 163
• Publication Date: 2017-03
• Subjects: calciphylaxis -- case report -- vitamin D -- ulcer -- calcium; Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.1177/1203475416668162
• Languages: English
• ISSNs: 1203-4754

Abstract

Background: Calciphylaxis is a rare disorder that is very unusual outside the setting of end-stage kidney disease. Case Summary: A 64-year-old woman with normal renal function presented with painful leg ulcers. She had previously received 300 000 IU of vitamin D3 followed by daily calcium and vitamin D3 supplementation. A skin biopsy was consistent with calciphylaxis, and she was treated with sodium thiosulphate infusions and wound debridement. Conclusion: Calcium and vitamin D3 supplements are widely prescribed. We report a case of calciphylaxis triggered by calcium and vitamin D3 supplementation in a patient with none of the typical risk factors. Our patient had an excellent response to treatment with sodium thiosulphate.