A case of non-O1/non-O139 Vibrio cholerae septicemia and meningitis in a neonate. (June 2015)

• Record Type: Journal Article
• Authors: Hao, Yingying; Wang, Yueling; Bi, Zhenwang; Sun, Baixiu; Jin, Yan; Bai, Yuanyuan; Chen, Baoli; Shao, Chunhong; Sun, Xuerong; Lu, Zhiming
• Is Part Of: International journal of infectious diseases. Volume 35(2015:Jun.)
• Page Start: 117
• Page End: 119
• Publication Date: 2015-06
• Subjects: Septicemia -- Meningitis -- Neonate -- Non-O1/non-O139 Vibrio cholerae; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2015.05.004
• Languages: English
• ISSNs: 1201-9712

Abstract

Highlights: We report a rare case of septicemia with meningitis due to non-O1/non-O139 Vibrio cholerae in a neonate. We examined the genotype and phenotype of the isolate in relation to pathogenicity. Multilocus sequence typing (MLST) was performed to establish the genetic heterogeneity of the isolate. Non-O1/non-O139 Vibrio cholerae should be added to the differential diagnosis of neonatal septicemia and meningitis. Summary: A case of septicemia with meningitis due to non-O1/non-O139 Vibrio cholerae in a neonate is reported. The genotype and phenotype of the isolate were examined in relation to the major virulence genes. The isolate was shown to be non-toxin but cytotoxin-producing, distinguished from the dominant clone of non-O1/non-O139 V. cholerae by multilocus sequence typing.