Characterisation of the nonlinear elastic behaviour of guinea pig tympanic membrane using micro-fringe projection. (2015)

• Record Type: Journal Article
• Authors: Liang, Junfeng; Fu, Boshen; Luo, Huiyang; Nakmali, Don; Gan, Rong Zhu; Lu, Hongbing
• Is Part Of: International journal of experimental and computational biomechanics. Volume 3:Number 4(2015)
• Page Start: 319
• Page End: 344
• Publication Date: 2015
• Subjects: guinea pigs -- tympanic membrane -- micro-fringe projection -- finite element method -- FEM -- static pressure -- volume displacement -- hyperelastic modelling -- nonlinear elastic behaviour -- acoustic transmission -- ears -- surface profile -- volume deformation -- stress -- strain; Human mechanics -- Periodicals; Biomechanics -- Computer simulation -- Periodicals; Biomechanics -- Methodology -- Periodicals; 612.76
• Languages: English
• ISSNs: 1755-8735

Abstract

Mechanical properties of tympanic membrane (TM) are crucial inputs for modelling acoustic transmission through the ear. In this paper a combined experimental and numerical approach was used to determine the mechanical properties of guinea pig TM under quasi-static condition based on the response of the TM to static pressure. A guinea pig bulla was prepared and the intact TM was subjected to both positive and negative pressures while its topography was measured using the micro-fringe projection technique. Images of the deformed TM were acquired and processed with a phase-shift method to reconstruct the surface profile and determine the volume deformation of the TM under pressures. Finite element method with the implementation of a hyperelastic model was established. The simulated TM deformations under applied pressures demonstrated a good agreement with the measured curves of the pressure-volume displacement relationship. The Young's modulus of guinea pig TM from seven bullas was determined as 15.2-28.3 MPa up to a strain level of 25%, and it changes with stress or strain.