Experimental characterization of an implantable neuro-packaging for EEG signal recording and measurement. (February 2016)

• Record Type: Journal Article
• Authors: Lay-Ekuakille, A.; Griffo, G.; Massaro, A.; Spano, F.; Gigli, G.
• Is Part Of: Measurement. Volume 79(2016:Feb.)
• Page Start: 321
• Page End: 330
• Publication Date: 2016-02
• Subjects: Neuro-packaging -- Nanomaterial -- Implantable device -- Biomedical measurement -- Temperature characterization -- EEG signal recording; Weights and measures -- Periodicals; Measurement -- Periodicals; Measurement; Weights and measures; Periodicals; 530.8
• DOI: 10.1016/j.measurement.2015.09.022
• Languages: English
• ISSNs: 0263-2241

Abstract

Highlights: A bio-implantable neuro-packaging for embedding neuro-recording EEG system is designed. A neuro-packaging is fabricated using PLA (poly lactic acid) biosorbable material. A thermal testing is carried out to verify the packaging behavior. To overcome PLA limitations, a nanotechnology approach is proposed. Abstract: There is a strong demand of implantable devices for diverse applications. Most of them are dedicated and are used for therapy activators, and others for monitoring physiological parameters. The aforementioned demand must be correlated to the utilization of new materials and their reliability during use. This research proposes a design of a complete implantable packaging for encompassing neuro-recording electroencephalogram signals. The content of all system is also illustrated in terms of inner devices and simulated in terms of thermal behavior. Finally the neuro-packaging has been built in polylactic acid and tested in appropriate experimental setup for a specific characterization by measuring temperature, humidity and deformation. However, since PLA is a biosorbable polymer, a further design has been performed covering the neuro-packaging with another biocompatible nanomaterial called ultra-high-molecular-weight polyethylene in order to avoid the bioabsorption.