Adjuvant Treatment for Older Women with Invasive Breast Cancer. (January 2016)

• Record Type: Journal Article
• Authors: Jolly, Trevor A; Williams, Grant R; Bushan, Sita; Pergolotti, Mackenzi; Nyrop, Kirsten A; Jones, Ellen L; Muss, Hyman B
• Is Part Of: Women's health. Volume 12:Number 1(2016)
• Page Start: 129
• Page End: 146
• Publication Date: 2016-01
• Subjects: adjuvant chemotherapy -- breast cancer -- elderly -- endocrine therapy -- geriatric assessment -- geriatric oncology -- radiation; Gynecology -- Periodicals; Obstetrics -- Periodicals; Women -- Health and hygiene -- Periodicals; 618.05
• DOI: 10.2217/whe.15.92
• Languages: English
• ISSNs: 1745-5057

Abstract

Older women experience a large share of breast cancer incidence and death. With the projected rise in the number of older cancer patients, adjuvant chemo-, radiation and endocrine therapy management will become a key component of breast cancer treatment in older women. Many factors influence adjuvant treatment decisions including patient preferences, life expectancy and tumor biology. Geriatric assessment predicts important outcomes, identifies key deficits, and can aid in the decision making process. This review utilizes clinical vignettes to illustrate core principles in adjuvant management of breast cancer in older women and suggests an approach incorporating life expectancy and geriatric assessment.