Approach to chemotherapy-associated thrombosis. (April 2015)

• Record Type: Journal Article
• Authors: Oppelt, Peter; Betbadal, Anthony; Nayak, Lalitha
• Is Part Of: Vascular medicine. Volume 20:Number 2(2015:Apr.)
• Page Start: 153
• Page End: 161
• Publication Date: 2015-04
• Subjects: angiogenesis inhibitors -- anticoagulants -- endothelial cells -- pulmonary embolism -- review -- thromboembolism -- thrombosis -- venous thrombosis; Blood-vessels -- Diseases -- Periodicals; Peripheral vascular diseases -- Periodicals; Vascular Diseases -- Periodicals; Vaisseaux sanguins -- Maladies -- Périodiques; Maladies vasculaires périphériques -- Périodiques; 616.13
• DOI: 10.1177/1358863X14568705
• Languages: English
• ISSNs: 1358-863X

Abstract

Treatment of cancer patients with antineoplastic agents is associated with a heightened risk of thrombotic events, both arterial and venous. In this article, we review the specific agents that are implicated and the pathophysiological processes that are known to be associated with this prothrombotic state. We conclude with current recommendations for prophylactic antithrombotic therapy in these clinical situations.