Hernia of the swim bladder (aerocystocele) with concurrent mycotic granulomatous inflammation and swim bladder carcinoma in a wild mullet (Mugil cephalus). (November 2016)

• Record Type: Journal Article
• Authors: Sirri, Rubina; Bianco, Carlo; Zuccaro, Gaetano; Turba, Maria Elena; Mandrioli, Luciana
• Is Part Of: Journal of veterinary diagnostic investigation. Volume 28:Number 6(2016:Nov.)
• Page Start: 739
• Page End: 743
• Publication Date: 2016-11
• Subjects: Epithelial neoplasm -- fish -- fungi -- granuloma -- hernia -- swim bladder; Veterinary medicine -- Diagnosis -- Periodicals; 636.0896075
• DOI: 10.1177/1040638716663600
• Languages: English
• ISSNs: 1040-6387

Abstract

We describe a hernia of the swim bladder, with a concurrent mycotic granulomatous inflammation, and carcinoma of the swim bladder in a wild mullet ( Mugil cephalus ) referred for an exophytic dorsal mass. Grossly, the mass was white, soft, and composed of multiple cystic gas-containing chambers connected by a funnel-shaped tissue segment to the coelomic swim bladder. Histologically, the mass was characterized by cysts of variable size, multifocally contiguous with the subepithelial rete mirabile, supported by abundant fibrous tissue. The skin covering the herniated swim bladder was focally ulcerated and replaced by abundant granulation tissue in which multiple scattered granulomas centered on pigmented fungal hyphae were observed. These granulomas were also seen in the remaining coelomic portion of the swim bladder as well as in the spleen, perivisceral pancreas, and peritoneal adipose tissue; the fungus was molecularly identified as Cladosporium spp. Focally, arising from the herniated swim bladder epithelium, an unencapsulated poorly demarcated, moderately cellular neoplasm, composed of islands, lobules, and acini of neoplastic epithelium, was found.