Inhibition effects of polysaccharides on HBV replication and cell proliferation from Lentinus edodes waste material. (October 2018)

• Record Type: Journal Article
• Authors: Jiao, Fengping; Li, Dong; Yang, Shulin; Zhang, Jianjun; Zhang, Chen; Jia, Le
• Is Part Of: Microbial pathogenesis. Volume 123(2018)
• Page Start: 461
• Page End: 466
• Publication Date: 2018-10
• Subjects: Pathogenic microorganisms -- Periodicals; Pathology, Molecular -- Periodicals; Communicable Diseases -- microbiology -- Periodicals; Communicable Diseases -- parasitology -- Periodicals; Micro-organismes pathogènes -- Périodiques; Pathologie moléculaire -- Périodiques; Electronic journals; 616.9041
• DOI: 10.1016/j.micpath.2018.08.004
• Languages: English
• ISSNs: 0882-4010

Abstract

Highlights: PLWM inhibited the secretion of HBsAg and HBeAg. PLWM had no effect on the inhibition of HBV DNA replication, but 50 µg/ml PLWM strengthened the inhibition effect on HBV DNA replications of Lamivudine (10 µmol/l). PLWM could inhibit cell proliferation and affect the expression of some anti-apoptosis proteins.