Placental Massive Perivillous Fibrinoid Deposition Associated with Coxsackievirus A16—Report of a Case, and Review of the Literature. (September 2016)

• Record Type: Journal Article
• Authors: Heller, Debra S.; Tellier, Raymond; Pabbaraju, Kanti; Wong, Sallene; Faye-Petersen, Ona M.; Muehlenbachs, Atis; Goldsmith, Cynthia; Denison, Amy; Zaki, Sherif R.
• Is Part Of: Pediatric and developmental pathology. Volume 19:Number 5(2016)
• Page Start: 421
• Page End: 423
• Publication Date: 2016-09
• Subjects: Coxsackievirus A16 infection -- hand-foot-mouth disease -- intrauterine fetal death -- massive placental perivillous fibrinoid deposition; Pediatric pathology -- Periodicals; Children -- Diseases -- Periodicals; Diagnosis, Laboratory -- Periodicals; Abnormalities, Human -- Periodicals; Child development -- Periodicals; Pediatrics -- Periodicals; 616.07
• DOI: 10.2350/15-10-1726-CR.1
• Languages: English
• ISSNs: 1093-5266

Abstract

Massive placental perivillous fibrinoid deposition in the placenta is thought to be an immune-related condition associated with poor perinatal outcomes, including growth restriction and intrauterine fetal demise, with a high risk of recurrence. Rare cases have been associated with Coxsackievirus infection. We present such a case and review the literature.