An Infant with a Diagnostically Challenging Hepatic Teratoma, Hypofibrinogenemia, and Adrenal Neuroblastoma: Case Report. (May 2015)

• Record Type: Journal Article
• Authors: Fried, Iris; Rom-Gross, Eitan; Finegold, Milton; Simanovsky, Natalia; Revel-Vilk, Shoshana; Ben-Neriah, Ziva; Weintraub, Michael; Pappo, Orit; Meir, Karen
• Is Part Of: Pediatric and developmental pathology. Volume 18:Number 3(2015)
• Page Start: 251
• Page End: 256
• Publication Date: 2015-05
• Subjects: hepatoblastoma -- hypofibrinogenemia -- liver tumor -- neuroblastoma -- teratoma; Pediatric pathology -- Periodicals; Children -- Diseases -- Periodicals; Diagnosis, Laboratory -- Periodicals; Abnormalities, Human -- Periodicals; Child development -- Periodicals; Pediatrics -- Periodicals; 616.07
• DOI: 10.2350/13-08-1361-CR.1
• Languages: English
• ISSNs: 1093-5266

Abstract

Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.