Cd2+-triggered amide tautomerization produces a highly Cd2+-selective fluorescent sensor across a wide pH range. (October 2016)

• Record Type: Journal Article
• Authors: Liu, Yang; Qiao, Qinglong; Zhao, Miao; Yin, Wenting; Miao, Lu; Wang, Liqiu; Xu, Zhaochao
• Is Part Of: Dyes and pigments. Volume 133(2016)
• Page Start: 339
• Page End: 344
• Publication Date: 2016-10
• Subjects: Amide tautomerization -- Fluorescent sensor -- Cadmium ions -- Wide pH range -- Cells imaging; Dyes and dyeing -- Periodicals; Pigments -- Periodicals; 667.2
• DOI: 10.1016/j.dyepig.2016.06.017
• Languages: English
• ISSNs: 0143-7208

Abstract

Abstract: An NBD-derived fluorescent sensor termedCdTS was reported to sense Cd 2+ with very high binding selectivity and significant fluorescence turn-on signal selectivity (65 fold enhancement). The amide/di-2-picolylamine receptor binds Cd 2+ in an imidic acid tautomeric form, but binds most of other metal ions in an amide tautomeric form. The transformable ability makesCdTS have the specific selectivity for Cd 2+ . Additionally, CdTS can fluoresently and colorimetricly recognize Cd 2+ across a wide pH range from 4.5 to 11.5. Finally, we appliedCdTS to detect Cd 2+ in living cells. Graphical abstract: CdTS can fluoresently recognize Cd 2+ across a wide pH range. Highlights: Cd 2+ can trigger amide tautomerization in the amide-DPA receptor. The probe is extremely sensitive to Cd 2+ with 65-fold emission enhancement. The probe has an excellent selectivity for Cd 2+ . The probe can recognize Cd 2+ across a wide pH range from 4.5 to 11.5. The probe can image Cd 2+ in living cells.