Asymmetric Diels–Alder cycloadditions of benzofulvene-based 2, 4-dienals via trienamine activation. Issue 18 (15th August 2018)

• Record Type: Journal Article
• Authors: Yue, Jing-Fei; Ran, Guang-Yao; Yang, Xing-Xing; Du, Wei; Chen, Ying-Chun
• Is Part Of: Organic chemistry frontiers. Volume 5:Issue 18(2018)
• Page Start: 2676
• Page End: 2679
• Publication Date: 2018-08-15
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c8qo00653a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A new type of 2, 4-dienal featuring a benzofulvene skeleton is utilised in asymmetric Diels–Alder cycloadditions with 3-olefinic oxindoles via trienamine catalysis. Abstract : A new type of 2, 4-dienal with α-substitutions and featuring a benzofulvene skeleton has been designed and utilised in asymmetric Diels–Alder cycloaddition reactions with 3-olefinic oxindoles under the trienamine catalysis of a chiral secondary amine. An array of chiral polyhydrofluorene frameworks with complex molecular structures are constructed efficiently, generally in fair to high yields with good diastereoselectivity and excellent enantioselectivity.