Dual responsive salen-type Schiff bases for the effective detection of l-arginine via a static quenching mechanism. (10th July 2018)

• Record Type: Journal Article
• Authors: Mohan, Nithya; Sreejith, S. S.; Begum, P. M. Sabura; Kurup, M. R. Prathapachandra
• Is Part Of: New journal of chemistry. Volume 42:Number 15(2018)
• Page Start: 13114
• Page End: 13121
• Publication Date: 2018-07-10
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c8nj02657b
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : The effect of substituents of salen Schiff bases on the detection ofl -arginine via a static quenching mechanism is discussed. Abstract : l -Arginine is one of the most important amino acids and plays a key role in diagnostic studies. Herein, we report four salen-type Schiff base fluorimetric/colorimetric sensors for the rapid detection ofl -arginine. Substituents play a major role in the sensing mechanism of probes with the nitro-substituent bearing probe showing the highest efficiency. A 1 : 2 complexation between all the probes and the analyte was evidenced from the absorption titrations; and the fluorescence studies revealed a quenching phenomenon occurring during complex formation. From the life time measurements, the nature of quenching was found to be static and the formation of a ground state complex was confirmed. DFT calculations done at the B3LYP/TZVP level of theory corroborated the experimental findings and further established the proton transfer from the probe to the analyte during the complex formation.