Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core–shell mesoporous silica nanoparticles. Issue 31 (16th July 2015)

• Record Type: Journal Article
• Authors: Saint-Cricq, P.; Deshayes, S.; Zink, J. I.; Kasko, A. M.
• Is Part Of: Nanoscale. Volume 7:Issue 31(2015)
• Page Start: 13168
• Page End: 13172
• Publication Date: 2015-07-16
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c5nr03777h
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : Core–shell Fe3 O4 @SiO2 mesoporous silica nanoparticles coated with a thermodegradable polymer allowed the release of a model drug through heating caused by a high frequency oscillating magnetic field. The polymer was made of poly(ethylene glycol) (PEG) functionalised with azo bonds that break with an elevation of temperature. Abstract : Core–shell Fe3 O4 @SiO2 mesoporous silica nanoparticles coated with a new thermodegradable polymer allowed the release of a model drug through heating caused by a high frequency oscillating magnetic field. The thermodegradable polymer was made of poly(ethylene glycol) (PEG) functionalised with azo bonds that break with an elevation of temperature.