Semicrystalline Polymers: Stepwise Drug‐Release Behavior of Onion‐Like Vesicles Generated from Emulsification‐Induced Assembly of Semicrystalline Polymer Amphiphiles (Adv. Funct. Mater. 29/2015). (3rd August 2015)

• Record Type: Journal Article
• Authors: Park, Mi‐Kyoung; Jun, Sangmi; Kim, Inhye; Jin, Seon‐Mi; Kim, Jin‐Gyu; Shin, Tae Joo; Lee, Eunji
• Is Part Of: Advanced functional materials. Volume 25:Number 29(2015)
• Page Start: 4561
• Page End: 4561
• Publication Date: 2015-08-03
• Subjects: electron tomography -- hydrolytic degradation -- onion‐like vesicles -- self‐assembly -- semicrystalline polymers; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201570195
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : On page 4570, E. Lee and team demonstrate the fabrication of aqueous onion‐like vesicles with multi‐walls based on the controlled assembly of biocompatible and degradable semicrystalline polymers (PEO‐b‐PCL). The multi‐walled vesicles formed by emulsion droplet instability lead to high drug‐loading capacity and stepwise drug‐releasing behavior through sequential hydrolytic degradation from the outermost to innermost wall.