A patient-specific follow up study of the impact of thoracic endovascular repair (TEVAR) on aortic anatomy and on post-operative hemodynamics. (15th December 2016)

• Record Type: Journal Article
• Authors: Gallo, Diego; Lefieux, Adrien; Morganti, Simone; Veneziani, Alessandro; Reali, Alessandro; Auricchio, Ferdinando; Conti, Michele; Morbiducci, Umberto
• Is Part Of: Computers & fluids. Volume 141 (2016)
• Page Start: 54
• Page End: 61
• Publication Date: 2016-12-15
• Subjects: Bird beak configuration -- Morphometry -- Computational fluid dynamics -- Wall shear stress -- Helical flow -- Thoracic aorta; Fluid dynamics -- Data processing -- Periodicals; 532.050285
• DOI: 10.1016/j.compfluid.2016.04.025
• Languages: English
• ISSNs: 0045-7930

Abstract

Highlights: Computational analysis of a TEVAR patient pre-op, post-op, and one-year follow up. We focus on geometrical features like curvature, torsion, and area variations. We focus on near wall and intravascular flow-related quantities (WSS and helicity). Partial restoration of normal flow in the region of interest is indicated. Overall efficacy of computational tools for TEVAR long-term impact is demonstrated. Abstract: Thoracic endovascular repair (TEVAR) is a minimally invasive alternative to classical open-chest surgery for pathologies of thoracic aorta such as aneurysms or dissections. It consists of the deployment of one or more endografts to either exclude aneurysms pressurization or seal entry tears of dissection. It is a minimally invasive procedure, yet long-term efficacy is still to be demonstrated and analyzed, depending on the geometry and the consequent hemodynamics and remodeling induced by the intervention. In this paper we consider a TEVAR patient by an extensive computational analysis of pre-op, post-op, and one-year follow up data. We focus on both geometrical features like curvature, torsion and area variations, as well as near-wall and intravascular flow-related quantities (i.e., wall shear stress-based descriptors and helicity). Comparison of the different morphologies indicates a partial restoration of normal flow in the region of interest, even though low WSS are still present with the associated risks. Overall, this study demonstrates the efficacy of quantitative computational tools in understanding the long-term impact of TEVAR.