A 15-year experience of two hundred and twenty five consecutive right hepatectomies. Issue 1 (January 2017)

• Record Type: Journal Article
• Authors: Levi Sandri, Giovanni Battista; Colasanti, Marco; Vennarecci, Giovanni; Santoro, Roberto; Lepiane, Pasquale; Mascianà, Gianluca; de Werra, Edoardo; Meniconi, Roberto Luca; Campanelli, Alessandra; Scotti, Andrea; Burocchi, Mirco; Di Castro, Angelo; D'Offizi, Giampiero; Antonini, Mario; Busi Rizzi, Elisa; Ialongo, Pasquale; Garufi, Carlo; Ettorre, Giuseppe Maria
• Is Part Of: Digestive and liver disease. Volume 49:Issue 1(2017)
• Page Start: 50
• Page End: 56
• Publication Date: 2017-01
• Subjects: Right hepatectomy -- Liver surgery -- Colorectal metastases -- Hepatocellular carcinoma -- Major liver resection; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; 616.33005
• DOI: 10.1016/j.dld.2016.09.014
• Languages: English
• ISSNs: 1590-8658

Abstract

Abstract: Background: In case of liver tumor, surgical resection is the therapeutic gold standard to increase patient survival. Among liver resections, right hepatectomy (RH) is defined as a major hepatectomy. The first aim of this study was to analyze the overall morbidity and mortality of patients undergoing RH, the second aim was to assess changes in both patients characteristic and surgical parameters and mortality rates in a single center institution. Materials: From 2001 to December 2015, 225 RH were performed in our center. We analyzed two time period: 2001–2007 and 2008–2015. Results: Ninety days post operative mortality was observed in 9 cases (4%) for the overall cohort. We observed a difference between the two groups in the use of Pringle Maneuver (p < 0, 001). This result is consistent in each major surgical indication: HCC (p = 0, 001), CLM (p = 0, 015) and BT (p = 0, 015). The estimated blood losses improved (p = 0, 028), particularly for the HCC cases (p = 0, 024). No difference was observed in terms of number of transfusions received between the two groups. Reduced length of stay was observed in the second group (p < 0, 001), more markedly for CLM cases (p = 0, 001). Conclusion: To further improve the outcomes of RH, it is important to performed this major hepatectomy in hepatobiliary centers with an overall liver resection experience of at least few hundred cases.