Efficient synthesis of a new compound family, 9-aryl-5H-imidazo[2, 1-d][1, 2, 5]triazepin-6(7H)-ones. Issue 35 (1st September 2016)
- Record Type:
- Journal Article
- Title:
- Efficient synthesis of a new compound family, 9-aryl-5H-imidazo[2, 1-d][1, 2, 5]triazepin-6(7H)-ones. Issue 35 (1st September 2016)
- Main Title:
- Efficient synthesis of a new compound family, 9-aryl-5H-imidazo[2, 1-d][1, 2, 5]triazepin-6(7H)-ones
- Authors:
- Földesi, Tamás
Dancsó, András
Simig, Gyula
Volk, Balázs
Milen, Mátyás - Abstract:
- Abstract: Representatives of a new compound family, 9-aryl-5 H -imidazo[2, 1- d ][1, 2, 5]triazepin-6(7 H )-ones have been synthesized. As structural analogues of biologically active 1-aryl-2, 3-benzodiazepine-4-ones, these compounds are potential drug candidates in the diseases of the central nervous system. An efficient five-step synthesis starting from imidazole is described here for the preparation of the target compounds. Shorter routes have also been studied, however, these attempts failed. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 72:Issue 35(2016)
- Journal:
- Tetrahedron
- Issue:
- Volume 72:Issue 35(2016)
- Issue Display:
- Volume 72, Issue 35 (2016)
- Year:
- 2016
- Volume:
- 72
- Issue:
- 35
- Issue Sort Value:
- 2016-0072-0035-0000
- Page Start:
- 5427
- Page End:
- 5432
- Publication Date:
- 2016-09-01
- Subjects:
- Nitrogen heterocycles -- Selectivity -- Ring closure -- Benzodiazepines -- Isosteres
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2016.07.029 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7511.xml