A new dual-function fluorescent probe of Fe3+ for bioimaging and probe-Fe3+ complex for selective detection of CN−. Issue 29 (21st July 2016)

• Record Type: Journal Article
• Authors: Yan, Lirun; Yang, Meipan; Leng, Xin; Zhang, Ming; Long, Ying; Yang, Bingqin
• Is Part Of: Tetrahedron. Volume 72:Issue 29(2016)
• Page Start: 4361
• Page End: 4367
• Publication Date: 2016-07-21
• Subjects: Fluorescent probe -- Fe3+ -- CN− -- Bioimaging; CRLHTAWDWGXVJZ-UHFFFAOYSA-N -- OAVULPOOAHQYDZ-UHFFFAOYSA-N; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2016.05.082
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: A rhodamine-based probe for Fe 3+ was prepared and confirmed by X-ray crystallography. The probe exhibited highly selective and sensitive recognition toward Fe 3+ with distinct color change. Interestingly, the probe-Fe 3+ complex could detect CN − according to the strong co-ordination ability of cyanide to Fe 3+ . The whole recognition mechanism was explored through Job's plot, MS data and theoretical calculations. Importantly, the probe was further used for detecting Fe 3+ in living cells and mouse, which exhibited excellent fluorescence imaging. Graphical abstract: