Hemophagocytic Lymphohistiocytosis in a Patient With Hodgkin lymphoma and Concurrent EBV, CMV, and Candida Infections. (January 2017)

• Record Type: Journal Article
• Authors: Mustafa Ali, Moaath; Ruano Mendez, Ana Lucia; Carraway, Hetty E.
• Is Part Of: Journal of investigative medicine high impact case reports. Volume 5:Number 1(2017)
• Publication Date: 2017-01
• Subjects: hemophagocytic lymphohistiocytosis -- Hodgkin lymphoma -- Epstein-Barr virus -- cytomegalovirus -- Candida; Internal medicine -- Periodicals; Medical care -- Periodicals; 616.005
• DOI: 10.1177/2324709616684514
• Languages: English
• ISSNs: 2324-7096

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome characterized by immune activation and subsequent widespread organ damage. Patients affected by HLH commonly develop fever, cytopenias, liver damage, neurologic manifestations, and hypercytokinemia. In this case, we describe a 60-year-old male who presented with HLH and concurrent Epstein-Barr virus, cytomegalovirus, and Candida infections and was subsequently diagnosed with a Hodgkin lymphoma. This case highlights the importance of considering a cancer diagnosis in the differential diagnosis of patients presenting with HLH.