Synthesis of substituted 3-methylene-2, 3-dihydrobenzofurans and 3-methylbenzofurans by rhodium (II)-catalyzed annulation. Issue 36 (9th September 2015) - Chen, Ying-Yu
Abstract: The selective synthesis of substituted 3-methylene-2, 3-dihydrobenzofurans and 3-methylbenzofurans has developed through Rh(II)-catalyzed denitrogenative annulation of N -sulfonyl-1, 2, 3-triazole at ambient to mild heating condition, respectively. Further, a one-pot strategy is also developed by using substituted O -propargylphenols through Cu/Rh-catalyzed method to rapidly construct 3-methylene-2, 3-dihydrobenzofuran derivatives. Graphical abstract: