Comparative evaluation of non-contrast CAIPIRINHA-VIBE 3T-MRI and multidetector CT for detection of pulmonary nodules: In vivo evaluation of diagnostic accuracy and image quality. Issue 1 (January 2016)

• Record Type: Journal Article
• Authors: Dewes, Patricia; Frellesen, Claudia; Al-Butmeh, Firas; Albrecht, Moritz H.; Scholtz, Jan-Erik; Metzger, Sarah C.; Lehnert, Thomas; Vogl, Thomas J.; Wichmann, Julian L.
• Is Part Of: European journal of radiology. Volume 85:Issue 1(2016)
• Page Start: 193
• Page End: 198
• Publication Date: 2016-01
• Subjects: CAIPIRINHA Controlled Aliasing In Parallel Imaging Results In Higher Acceleration -- CI confidence interval -- CNR contrast-to-noise ratio -- CT computed tomography -- GFR glomerular filtration rate -- HASTE half-Fourier acquisition single-shot turbo spin-echo -- ICC intraclass correlation coefficient -- MRI magnetic resonance imaging -- pMRI parallel MRI -- SAR signal absorption rates -- SNR signal-to-noise ratio -- VIBE volumetric interpolated breath-hold examination; Solitary pulmonary nodule -- Lung -- Magnetic resonance imaging -- Computed tomography; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2015.11.020
• Languages: English
• ISSNs: 0720-048X

Abstract

Abstract: Purpose: To evaluate the diagnostic accuracy, subjective image quality, and interobserver agreement of non-contrast Controlled Aliasing In Parallel Imaging Results In Higher Acceleration (CAIPIRINHA) volumetric interpolated breath-hold examination (VIBE) 3T magnetic resonance imaging (MRI) for the detection of pulmonary nodules with intra-individual comparison to computed tomography (CT). Materials and methods: We evaluated 54 patients (27 male, 27 female; mean age, 60.8 ± 11.5 years) who prospectively underwent thoracic 3T-MRI using CAIPIRINHA-VIBE sequences and chest CT. Diagnostic accuracy for the detection of lung nodules on CAIPIRINHA-VIBE MRI by three independent observers were compared to the reference standard CT. Subjective image quality was rated using a 5-point grading scale. Diagnostic accuracy was calculated and interobserver agreement was assessed using intraclass correlation coefficient (ICC). Results: Sensitivity of 3T-MRI for the detection of pulmonary lesions compared to CT was 88.1% (95% confidence interval [CI]: 0.81–0.93) and specifity was 79.1% (95% CI: 0.50–0.95). Sensitivity for lesions <5 mm was 77.2% (95% CI: 0.59–0.90) and for lesions from 5 to 10 mm was 87.2% (95% CI: 0.76–0.94). Sensitivity for lesions >10 mm was 100%. Observer ratings regarding subjective image quality were good to excellent for 3T-MRI (1.54) and CT (1.14) with almost perfect interobserver agreement for 3T-MRI and CT (ICC = 0.83, 95% CI: 0.78–0.89; ICC = 0.89, 95% CI: 0.85–0.94). Conclusions: Non-contrast CAIPIRINHA-VIBE 3T-MRI allows for the reliable detection of pulmonary lesions with a diameter >5 mm in comparison with chest CT with high diagnostic accuracy, subjective image quality, and interobserver agreement.