Immunoglobulin G4-positive staining of orbital lesions in thyroid eye disease: Report of two cases. Issue 5 (3rd September 2018)

• Record Type: Journal Article
• Authors: Takahashi, Yasuhiro; Takahashi, Emiko; Hiromatsu, Yuji; Kakizaki, Hirohiko
• Is Part Of: Modern rheumatology. Volume 28:Issue 5(2018)
• Page Start: 893
• Page End: 896
• Publication Date: 2018-09-03
• Subjects: Histopathology -- Immunoglobulin G4-related ophthalmic disease -- Steroid -- Thyroid eye disease; Rheumatology -- Periodicals; 616.723005
• DOI: 10.3109/14397595.2016.1174421
• Languages: English
• ISSNs: 1439-7595

Abstract

Abstract: We report two cases with immunoglobulin G4 (IgG4)-positive staining of orbital lesions and thyroid eye disease (TED). Case 1 was a 63-year-old male with right upper eyelid swelling due to right lacrimal gland enlargement. Case 2 was a 49-year-old male with bilateral proptosis due to multiple orbital masses. Both the biopsied right lacrimal gland in Case 1 and the orbital masses on both sides in Case 2 showed infiltration of immunoglobulin-G4-positive plasma cells.