Dynamic measurement of newly formed carbonyl compounds in vapors from electronic cigarettes. Issue 2 (April 2017)

• Record Type: Journal Article
• Authors: Sala, Cecilia; Medana, Claudio; Pellegrino, Raffaele; Aigotti, Riccardo; Bello, Federica Dal; Bianchi, Giancarlo; Davoli, Enrico
• Is Part Of: European journal of mass spectrometry. Volume 23:Issue 2(2017)
• Page Start: 64
• Page End: 69
• Publication Date: 2017-04
• Subjects: E-cigarettes -- SPME GC/MS -- acrolein -- smoking machine; Mass spectrometry -- Periodicals; Mass Spectrometry; Mass spectrometry; Periodicals; Periodicals; 543.6505
• DOI: 10.1177/1469066717699078
• Languages: English
• ISSNs: 1469-0667

Abstract

Recently, the formation of carbonyl compound within e-cigarettes usage has been reported. The aim of this study was to develop a new analytical method for the direct analysis of carbonyl compounds in vaporized liquids. Two different types of e-cigarettes and different puff's duration have been evaluated, using a modified smoking machine for vapor generation. An isotopic dilution approach, based on deuterated internal standard addition to the e-liquid before filling the e-cigarette tank, has been developed. Carbonyl compounds have been sampled in vapors using a direct, simple, solid-phase microextraction technique with on-fiber derivatization. Related oximes have been analyzed by gas chromatography/mass spectrometry technique. Results confirmed that new carbonyl compounds are formed during the vaping process, and that formation depends both from the heating device and from puffing topography.