Enantioselective palladium-catalyzed addition of malonates to 3, 3-difluoropropenes. Issue 41 (11th October 2018)
- Record Type:
- Journal Article
- Title:
- Enantioselective palladium-catalyzed addition of malonates to 3, 3-difluoropropenes. Issue 41 (11th October 2018)
- Main Title:
- Enantioselective palladium-catalyzed addition of malonates to 3, 3-difluoropropenes
- Authors:
- Drouin, Myriam
Paquin, Jean-François - Abstract:
- Abstract: Monofluoroalkenes bearing a malonate unit at the β position can be synthesized by the enantioselective addition of diesters to 3, 3-difluoropropenes. The difference in reactivity regarding the geometry and the substituents of the alkene of the 3, 3-difluoropropenes, as well as the alkyl groups of the malonates, was studied and limitations were identified. The reaction was also performed with different 3, 3-difluoropropenes. Further synthetic transformations of a newly functionalized monofluoroalkene were also accomplished. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 74:Issue 41(2018)
- Journal:
- Tetrahedron
- Issue:
- Volume 74:Issue 41(2018)
- Issue Display:
- Volume 74, Issue 41 (2018)
- Year:
- 2018
- Volume:
- 74
- Issue:
- 41
- Issue Sort Value:
- 2018-0074-0041-0000
- Page Start:
- 6023
- Page End:
- 6032
- Publication Date:
- 2018-10-11
- Subjects:
- Asymmetric synthesis -- Palladium catalysis -- Monofluoroalkene -- 3, 3-Difluoropropene -- Organofluorine chemistry
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2018.08.034 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7492.xml