Asymmetric synthesis of secondary benzylic alcohols via arene chromium tricarbonyl complexes. Issue 40 (4th October 2018)
- Record Type:
- Journal Article
- Title:
- Asymmetric synthesis of secondary benzylic alcohols via arene chromium tricarbonyl complexes. Issue 40 (4th October 2018)
- Main Title:
- Asymmetric synthesis of secondary benzylic alcohols via arene chromium tricarbonyl complexes
- Authors:
- da Costa, M. Rute G.
Curto, M. João M.
Davies, Stephen G.
Teixeira, Fátima C.
Thomson, James E. - Abstract:
- Abstract: (Aryl aldehyde)- and (aryl ketone)-chromium tricarbonyl complexes ortho -substituted with the chiral auxiliary O -methyl- N -(α-methylbenzyl)hydroxylamine undergo diastereoselective addition of Grignard reagents and Super-Hydride ®, respectively, to give the corresponding secondary alcohols in high diastereoisomeric purity. These compounds may be easily decomplexed and deprotected to give the corresponding enantiopure amino alcohols. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 74:Issue 40(2018)
- Journal:
- Tetrahedron
- Issue:
- Volume 74:Issue 40(2018)
- Issue Display:
- Volume 74, Issue 40 (2018)
- Year:
- 2018
- Volume:
- 74
- Issue:
- 40
- Issue Sort Value:
- 2018-0074-0040-0000
- Page Start:
- 5965
- Page End:
- 5973
- Publication Date:
- 2018-10-04
- Subjects:
- Arene chromium tricarbonyl -- Secondary alcohols -- Asymmetric synthesis -- Hydroxylamines
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2018.08.033 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7490.xml