Mediator Architecture and RNA Polymerase II Interaction. Issue 12 (19th June 2016)

• Record Type: Journal Article
• Authors: Plaschka, Clemens; Nozawa, Kayo; Cramer, Patrick
• Is Part Of: Journal of molecular biology. Volume 428:Issue 12(2016:Jun. 19)
• Page Start: 2569
• Page End: 2574
• Publication Date: 2016-06-19
• Subjects: Pol II RNA polymerase II -- EM electron microscopy; gene transcription -- RNA polymerase II -- coactivator -- multiprotein complex; Molecular biology -- Periodicals; Biology -- Periodicals; Biochemistry -- Periodicals; Bacteriology -- Periodicals; Molecular Biology -- Periodicals; Biochemistry -- Periodicals; Biologie moléculaire -- Périodiques; Biologie -- Périodiques; Biochimie -- Périodiques; Moleculaire biologie; Biochemistry; Biology; Molecular biology; Periodicals; 572.805
• DOI: 10.1016/j.jmb.2016.01.028
• Languages: English
• ISSNs: 0022-2836

Abstract

Abstract: Integrated structural biology recently elucidated the architecture of Mediator and its position on RNA polymerase II. Here we summarize these achievements and list open questions on Mediator structure and mechanism.