Configuration of the PRIMO software to simulate intensity modulated radiation therapy through dynalog file. (September 2016)

• Record Type: Journal Article
• Authors: Dias, Susana; Esposito, Alessandro; Silva, Sofia; Cunha, Luis T.; Dias, Anabela Gregório; Pimparel, Diana; Lencart, Joana; Santos, João A.M.
• Is Part Of: Physica medica. Volume 32(2016)Supplement 3
• Page Start: 316
• Publication Date: 2016-09
• Subjects: Medical physics -- Periodicals; Biophysics -- Periodicals; Biophysics -- Periodicals; Imagerie médicale -- Périodiques; Radiothérapie -- Périodiques; Rayons X -- Sécurité -- Mesures -- Périodiques; Physique -- Périodiques; Médecine -- Périodiques; 610.153
• DOI: 10.1016/j.ejmp.2016.07.193
• Languages: English
• ISSNs: 1120-1797

Abstract

Abstract : Introduction: Varian DynaLog files contain information on the Multi Leaf Collimator (MLC) actual configuration, and gantry and collimator angles during Intensity Modulated Radiation Therapy (IMRT). The Monte Carlo (MC) simulation of an actual IMRT procedure allows studying the dosimetric effect of possible mismatches between planned and actual delivery. The PRIMO software is a MC software targeted to External Radiotherapy environment. Nevertheless, IMRT is not part of the implemented options. Purpose: To configure PRIMO to simulate an actual IMRT procedure by DynaLog files manipulation. Materials and methods: A Varian 2300CD LINAC associated to a 120HD MLC was simulated. Static simulations were primarily performed to verify the LINAC and MLC models against experimental data. A dynamic irradiation with MLC modulation was split into a sequence of static segments. PRIMO was configured by introducing the DynaLog files information and the procedure was simulated on a solid water phantom. Gafchromic films were used to measure actual dose distribution and to compare it with the simulations through a 2D Gamma analysis. Results: More than 95% of Gamma points <1 were found in static simulations. PRIMO was efficiently configured to simulate an IMRT procedure based on the DynaLog file of the actual irradiation. Preliminary results showed up to 90.8% of Gamma points <1 with respect to the measurement. Conclusion: A workflow was developed to configure PRIMO to simulate IMRT through the direct introduction of DynaLog files. These results represent an initial study towards a clinically useful implementation of IMRT simulation using PRIMO. Disclosure: The authors have no relevant financial or nonfinancial relationships to disclose.