Chemotherapy: Multicombination Approach Suppresses Listeria monocytogenes‐Induced Septicemia‐Associated Acute Hepatic Failure: The Role of iRhom2 Signaling (Adv. Healthcare Mater. 17/2018). Issue 17 (5th September 2018)

• Record Type: Journal Article
• Authors: Xu, Min‐Xuan; Ge, Chen‐Xu; Qin, Yu‐Ting; Gu, Ting‐Ting; Lou, De‐Shuai; Li, Qiang; Hu, Lin‐Feng; Tan, Jun
• Is Part Of: Advanced healthcare materials. Volume 7:Issue 17(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-09-05
• Subjects: fisetin -- FN nanoparticles -- iRhom2 -- Listeria monocytogenes -- septicemia; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201870068
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : Biomaterials functionalized with nano‐scale drug carriers exhibit excellent biological properties. In article1800427, a novel design by Min‐Xuan Xu, Jun Tan, and co‐workers, highlights the latest advanced approach regarding the multicombination drug delivery for the chemoprevention of septicemia‐associated acute hepatic failure. The multifunctional nanoparticles can effectively suppress septicemia, systemic inflammatory response syndrome, and corresponding fatal hepatic injury by inhibition of oxidative stress and inflammation.