Effects of oral administration of different dosages of carvacrol essential oils on intestinal barrier function in broilers. Issue 5 (3rd July 2018)

• Record Type: Journal Article
• Authors: Liu, ShuDong; Song, MinHo; Yun, Won; Lee, JiHwan; Lee, ChangHee; Kwak, WooGi; Han, NamSoo; Kim, HyeunBum; Cho, JinHo
• Is Part Of: Journal of animal physiology and animal nutrition. Volume 102:Issue 5(2018)
• Page Start: 1257
• Page End: 1265
• Publication Date: 2018-07-03
• Subjects: broiler chicken -- carvacrol -- essential oils -- intestine barrier -- tight junction; Animal nutrition -- Periodicals; Feeds -- Periodicals; 636.085
• DOI: 10.1111/jpn.12944
• Languages: English
• ISSNs: 0931-2439

Abstract

Abstract: Essential oils are widely used in the pharmaceutical, food and cosmetic industries, and many plant essential oils have shown that they have positive effects on broilers nutrition. This experiment was conducted to study the effects of orally administered different dosages of carvacrol essential oils on intestinal barrier function in broiler chickens. A total of eighty 28‐day‐old (1.28 ± 0.15 kg) ROSS 308 broilers were randomly allocated to four groups of 20 replicates each, with one chicken per replicate per cage, and all were fed with the same diet. Four experimental groups were orally administered 0, 200, 300 or 400 μl carvacrol essential oils at 18:00 hr every day during the 2‐week experimental period. As a result of which, the gene expression of the occludin, claudin‐1, claudin‐5, ZO‐1 and ZO‐2 in intestinal mucosa of small intestine ( p < 0.05) and the goblet cell content in small intestine epithelium ( p < 0.05) were significantly increased; test subjects with 300 or 400 μl carvacrol essential oils reduced the microbial counts of Salmonella spp. and Escherichia coli in the intestines ( p < 0.05); Essential oils administration also significantly increased activity of the sucrase ( p < 0.05) and lactase ( p < 0.05) in intestinal mucosa. In conclusion, the carvacrol essential oils have positive effects on growth performance and intestinal barriers function of broilers; those effects may be related to the dosage, as administration of 300 or 400 μl was more effective than that of 200 μl.