Dehydration of CO2-α-cyclodextrin complex powder by desiccant adsorption method and its release properties. (16th November 2016)

• Record Type: Journal Article
• Authors: Ho, Thao M.; Howes, Tony; Bhandari, Bhesh R.
• Is Part Of: Journal of microencapsulation. Volume 33:Number 8(2016:Dec.)
• Page Start: 763
• Page End: 772
• Publication Date: 2016-11-16
• Subjects: Release properties -- relative humidity -- complex powder -- amorphous α-CD powder -- solid encapsulation; Microencapsulation -- Periodicals; Controlled release technology -- Periodicals; 615.19
• DOI: 10.1080/02652048.2016.1260662
• Languages: English
• ISSNs: 0265-2048

Abstract

Abstract: Stability and release properties of CO2 -α-cyclodextrin complex powder prepared by solid encapsulation (water activity, a w ≈ 0.95) followed by moisture removal using silica gel and CaCl2 desiccants during post-dehydration were investigated. The results showed that CaCl2 reduced a w much faster than silica gel did under the same conditions. After approximately 60 h, a w of complex powders reduced using silica gel was almost constant at 0.247 (±0.012), while those treated with CaCl2, a w was 0.225 (±0.005) and had not yet reached their lowest value. Moisture adsorption by silica gel and CaCl2 also led to a decrease in the CO2 concentration of complex powder (higher decrease for silica gel adsorption) without affecting the structure and morphology of complex powder. The CO2 release properties of CaCl2 - a w -reduced complex powder at different relative humidities (32.73, 52.86, 75.32 and 97.30% RH), liquid environments (water and oil) and packaging methods (normal and vacuum) were also studied.