Strongyloidiasis-Related IRIS: A Case Report and Literature Review. (January 2017)

• Record Type: Journal Article
• Authors: Bar-Yoseph, Haggai; Zohar, Yaniv; Lorber, Margalit
• Is Part Of: Journal of the International Association of Providers of AIDS Care. Volume 16:Number 1(2017:Jan./Feb.)
• Page Start: 8
• Page End: 10
• Publication Date: 2017-01
• Subjects: IRIS -- strongyloidiasis -- AIDS; AIDS (Disease) -- Periodicals; 616.9792
• DOI: 10.1177/2325957416673149
• Languages: English
• ISSNs: 2325-9574

Abstract

Helminthic infection and HIV have been reported to coexist, particularly in sub-Saharan African patients living with HIV. Strongyloidiasis is one of the most common helminths, usually leading to cutaneous and gastrointestinal (GI) symptoms. In the immunocompromised host, this infection can lead to strongyloidiasis hyperinfection syndrome (SHS), not common in HIV-infected patients. Immune reconstitution inflammatory syndrome (IRIS) can follow the initiation of antiretroviral therapy (ART), with a variety of presentations. The authors present here a 32-year-old HIV-infected female who was recently diagnosed with AIDS, started ART, and recovered from SHS. Her upper endoscopy revealed severe duodenitis but no causal agent per biopsy or stool examination. After receiving symptomatic therapy, she showed improvement, a course of events that fit the diagnosis of GI-related IRIS.