Ultralow dose CT for follow-up of solid pulmonary nodules: A pilot single-center study using Bland-Altman analysis. Issue 34 (August 2018)

• Record Type: Journal Article
• Authors: Paks, Michael; Leong, Paul; Einsiedel, Paul; Irving, Louis B.; Steinfort, Daniel P.; Pascoe, Diane M.
• Other Names: Li. Yan section editor.
• Is Part Of: Medicine. Volume 97:Issue 34(2018)
• Publication Date: 2018-08
• Subjects: chest CT -- iterative reconstruction -- lung nodule -- radiation dose reduction -- volumetry; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000012019
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : Abstract: Solid pulmonary nodules are a common finding requiring serial computed tomography (CT) imaging. We sought to explore the detection and measurement accuracy of an ultralow-dose CT (ULDCT) protocol compared with our standard low-dose CT (LDCT) nodule follow-up protocol. In this pragmatic single-center pilot prospective cohort study, patients scheduled for clinically indicated CT surveillance of 1 or more known solid pulmonary nodules >2 mm underwent ULDCT immediately after routine LDCT. The Bland-Altman 95% limits of agreement for diameter and volumetry were calculated. In all, 57 patients underwent 60 imaging episodes, with 170 evaluable nodules. ULDCT detected all known solid pulmonary nodules >2 mm. Bland-Altman analyses demonstrated clinically agreement for both nodule diameter and volume, both of which fell within prespecified limits. This single-center pilot study suggests that ULDCT may be of use in surveillance of known solid pulmonary nodules >2 mm.