Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists. Issue 4 (15th February 2016)

• Record Type: Journal Article
• Authors: Micheli, Fabrizio; Cremonesi, Susanna; Semeraro, Teresa; Tarsi, Luca; Tomelleri, Silvia; Cavanni, Paolo; Oliosi, Beatrice; Perdonà, Elisabetta; Sava, Anna; Zonzini, Laura; Feriani, Aldo; Braggio, Simone; Heidbreder, Christian
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 26:Issue 4(2016)
• Page Start: 1329
• Page End: 1332
• Publication Date: 2016-02-15
• Subjects: Dopamine -- Antagonist -- DA D3 receptor -- 7-TM -- Morpholine; Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2015.12.081
• Languages: English
• ISSNs: 0960-894X

Abstract

Graphical abstract: Abstract: A new series of morpholine derivatives has been identified as selective DA D3 receptor antagonists; their in vitro profile and pharmacokinetic data are provided.